Cortex
Volume 48, Issue 2 , Pages 156-165 , February 2012

Traumatic brain injury and the frontal lobes: What can we gain with diffusion tensor imaging?

  • Giuseppe Zappalà

      Affiliations

    • Behavioral Neurology Unit, Garibaldi Hospital, Catania, Italy
    • Corresponding Author InformationCorresponding author. Behavioral Neurology Unit, Garibaldi Hospital, Catania, Italy.
  • ,
  • Michel Thiebaut de Schotten

      Affiliations

    • NatBrainLab, Department of Forensic and Neurodevelopmental Sciences, Institute of Psychiatry, Kings College, London, UK
    • Inserm-UPMC, UMR S 975, G.H. Pitié-Salpetrière, Paris, France
  • ,
  • Paul J. Eslinger

      Affiliations

    • Department of Neurology (Center for MRI Research), Penn State Hershey Medical Center, Hershey, PA, USA
    • Department of Radiology (Center for MRI Research), Penn State Hershey Medical Center, Hershey, PA, USA

Received 14 December 2010 ,Revised 10 March 2011 ,Accepted 22 June 2011.

References 

  1. Amunts K, Kedo O, Kindler M, Pieperhoff P, Mohlberg H, Shah NJ, et al. Cytoarchitectonic mapping of the human amygdala, hippocampal region and entorhinal cortex: Intersubject variability and probability maps. Anatomy and Embryology. 2005;210(5–6):343–352
  2. Amunts K, Malikovic A, Mohlberg H, Schormann T, Zilles K. Brodmann’s areas 17 and 18 brought into stereotaxic space – where and how variable?. NeuroImage. 2000;11(1):66–84
  3. Amunts K, Schleicher A, Burgel U, Mohlberg H, Uylings HB, Zilles K. Broca’s region revisited: Cytoarchitecture and intersubject variability. Journal of Comparative Neurology. 1999;412(2):319–341
  4. Arfanakis K, Haughton VM, Carew JD, Rogers BP, Dempsey RJ, Meyerand ME. Diffusion tensor MR imaging in diffuse axonal injury. American Journal of Neuroradiology. 2002;23(5):794–802
  5. Assaf Y, Pasternak O. Diffusion tensor imaging (DTI)-based white matter mapping in brain research: A review. Journal of Molecular Neuroscience. 2008;26(8):1133–1144
  6. Basser PJ, Mattiello J, LeBihan D. MR diffusion tensor spectroscopy and imaging. Biophysics Journal. 1994;66(1):259–267
  7. Bazarian JJ, Zhong J, Blyth B, Zhu T, Kavcic V, Peterson D. Diffusion tensor imaging detects clinically important axonal damage after mild traumatic brain injury: A pilot study. Journal of Neurotrauma. 2007;24(9):1447–1459
  8. Beaulieu C. The biological basis of diffusion anisotropy. In:  Johansen-Berg H,  Behrens TE editor. Diffusion MRI: From Quantitative Measurement to In vivo Neuroanatomy. London: Elsevier; 2009;p. 105–126
  9. Bhullar I, Roberts E, Brown L, Lipei H. The effect of age on blunt traumatic brain-injured patients. American Surgery. 2010;76(9):966–968
  10. Catani M. Diffusion tensor magnetic resonance imaging tractography in cognitive disorders. Current Opinion in Neurology. 2006;19(6):599–606
  11. Catani M, Allin MP, Husain M, Pugliese L, Mesulam MM, Murray RM, et al. Symmetries in human brain language pathways correlate with verbal recall. Proceedings of National Academy of Sciences of the United States of America. 2007;104(43):17163–17168
  12. Catani M, ffytche DH. The rises and falls of disconnection syndromes. Brain. 2005;128(10):2224–2239
  13. Catani M, ffytche DH. New section: Cortex clinical neuroanatomy. Cortex. 2010;46(1):1
  14. Catani M, Howard RJ, Pajevic S, Jones DK. Virtual in vivo interactive dissection of white matter fasciculi in the human brain. NeuroImage. 2002;17(1):77–94
  15. Catani M, Thiebaut de Schotten M. A diffusion tensor imaging tractography atlas for virtual in vivo dissections. Cortex. 2008;44(8):1105–1132
  16. Catani M and Thiebaut de Schotten M. Atlas of Human Brain Connections. Oxford: Oxford University Press, 2012.
  17. Catani M, Dell'Acqua F, Vergani F, Malik F, Hodge H, Roy P, et al. Short frontal lobe connections of the human brain. Cortex. 2012;48(2):273–291
  18. Charlton R, Barrick TR, Lawes INC, Markus HS, Morris R. White matter pathways associated with working memory in normal aging. Cortex. 2010;46(4):474–489
  19. Cubillo A, Halari R, Smith A, Taylor E, Rubia K. A review of fronto-striatal and fronto-cortical brain abnormalities in children and adults with Attention Deficit Hyperactivity Disorder (ADHD) and new evidence for dysfunction in adults with ADHD during motivation and attention. Cortex. 2012;48(2):177–198
  20. Dejerine J. Anatomie des centres nerveux. Paris: Rueff et Cie; 1895;
  21. El-Sayed T, Mota A, Fraternali F, Ortiz M. Biomechanics of traumatic brain injury. Computer Methods in Applied Mechanics and Engineering. 2008;197:4692–4701
  22. Epelbaum S, Pinel P, Gaillard R, Delmaire C, Perrin M, Dupont S, et al. Pure alexia as a disconnection syndrome: New diffusion imaging evidence for an old concept. Cortex. 2008;44(8):962–974
  23. Eslinger P, Grattan L, Geder L. Impact of frontal lobe lesions on rehabilitation and recovery from acute brain injury. Neurorehabilitation. 1995;5(2):161–182
  24. Eslinger PJ, Zappalà G, Chakara F, Barrett AM. Cognitive impairments after traumatic brain injury. In: Brain Injury Medicine. New York: Demos; 2007;p. 45–56
  25. Gaetz M. The neurophysiology of brain injury. Clinical Neurophysiology. 2004;115(1):4–18
  26. Gennarelli TA, Thibault LE, Adams JH, Graham DI, Thompson CJ, Marcincin RP. Diffuse axonal injury and traumatic coma in the primate. Annals of Neurology. 1982;12(6):564–574
  27. Gouick J, Gentleman D. The emotional and behavioural consequences of traumatic brain injury. Trauma. 2004;6(4):285–292
  28. Gualtieri T. The problem of mild head injury. Neuropsychiatry, Neuropsychology and Behavioral Neurology. 1995;8:127–136
  29. Hashimoto K, Okumura A, Shinoda J, Abo M, Nakamura T. Tensor magnetic resonance imaging in a case of mild traumatic brain injury with lowered verbal intelligence quotient. Journal of Rehabilitation Medicine. 2007;39(5):418–420
  30. Henry JD, Philips LH, Crawford JR, Ietswaart M, Summers F. Theory of mind following traumatic brain injury: The role of emotion recognition and executive dysfunction. Neuropsychologia. 2006;44(10):1623–1628
  31. Hou DJ, Tong KA, Ashwal S, Oyoyo U, Joo E, Shutter L, et al. Diffusion-weighted magnetic resonance imaging improves outcome prediction in adult traumatic brain injury. Journal of Neurotrauma. 2007;24(10):1558–1569
  32. Hughes DG, Jackson A, Mason DL, Berry E, Hollis S, Yates DW. Abnormalities on magnetic resonance imaging seen acutely following mild traumatic brain injury: Correlation with neuropsychological tests and delayed recovery. Neuroradiology. 2004;46(7):550–558
  33. Huisman TA, Schwamm LH, Schaefer PW, Koroshetz WJ, Scetty-Alva N, Ozsunar Y, et al. Diffusion tensor imaging as potential biomarker of white matter injury in diffuse axonal injury. American Journal of Neuroradiology. 2004;25(3):370–376
  34. Inglese M, Makani S, Johnson G, Cohen BA, Silver JA, Gonen O, et al. Diffuse axonal injury in mild traumatic brain injury: A diffusion tensor imaging study. Journal of Neurosurgery. 2005;103(2):298–303
  35. Jang SH, Kim DS, Son SM, Cho YW, Kim SH, Kim OL, et al. Clinical application of tensor tractography for elucidation of the causes of motor weakness in patients with traumatic brain injury. Neurorehabilitation. 2009;24(3):273–278
  36. Jennett B. The problem of mild head injury. Practitioner. 1978;221(1321):77–82
  37. Jones DK. Studying connections in the living human brain with diffusion MRI. Cortex. 2008;44(8):936–952
  38. Kinnunen KM, Greenwood R, Powell JH, Leech R, Hawkins PC, Bonnelle V, et al. White matter damage and cognitive impairment after traumatic brain injury. Brain. 2011;134(2):449–463
  39. Kolb B, Whishaw IQ. Fundamentals of Human Neuropsychology. New York: Freeman & Co; 1990;
  40. Kraus MF, Susmaras T, Caughlin BP, Walker CJ, Sweeney JA, Little DM. White matter integrity and cognition in chronic traumatic brain injury: A diffusion tensor imaging study. Brain. 2007;130(10):2508–2519
  41. Krause M, Mahant N, Kotschet K, Fung VS, Vagg D, Wong CH, et al. Dysexecutive behaviour following deep brain lesions – A different type of disconnection syndrome. Cortex. 2012;48(1):97–119
  42. Langen M, Leemans A, Johnston P, Ecker C, Daly E, Murphy CM, et al. Fronto-striatal circuitry and inhibitory control in autism: Findings from diffusion tensor imaging tractography. Cortex. 2012;48(2):166–176
  43. Lawes INC, Barrick TR, Murugam V, Spierings N, Evans DR, Song M, et al. Atlas-based segmentation of white matter tracts of the human brain using diffusion tensor tractography and comparison with classical dissection. NeuroImage. 2008;39(1):62–79
  44. Lee B, Newberg A. Neuroimaging in traumatic brain injury. Journal of the American Society of Experimental Neurotherapeutics. 2005;2(2):372–383
  45. Levine B, Fujiwara E, O’Connor C, Richard N, Kovacevic N, Mandic M. In vivo characterization of traumatic brain injury neuropathology with structural and functional imaging. Journal of Neurotrauma. 2006;23(10):1396–1411
  46. Li XY, Feng DF. Diffuse axonal injury: Novel insights into detection and treatment. Journal of Clinical Neuroscience. 2009;16(5):614–619
  47. Lipton ML, Gulko E, Zimmermann ME, Friedman BW, Kim M, Gellella E, et al. Diffusion-tensor imaging implicates prefrontal axonal injury in executive function impairment following very mild traumatic brain injury. Radiology. 2009;252(3):816–824
  48. Lucas J. Traumatic brain injury and post-concussive syndrome. In:  Snyder PJ,  Nussbaum PD editor. Clinical Neuropsychology. Washington DC: APA; 1999;p. 243–265
  49. Marquez de La Plata CD, Garces J, Shokri Kojori E, Grinnan J, Krishnan K, Pidikiti R, et al. Deficits in functional connectivity of hippocampal and frontal lobe circuits after traumatic axonal injury. Archives of Neurology. 2011;68(1):74–84
  50. Mateer C, Sira C. Cognitive and emotional consequences of TBI: Intervention strategies for vocational rehabilitation. Neurorehabilitation. 2006;21(4):315–326
  51. McDonald S, Flanagan S. Social perception deficits after traumatic brain injury: Interaction between emotion recognition, mentalizing ability, and social communication. Neuropsychology. 2004;18(3):572–579
  52. Mesulam MM. From sensation to cognition. Brain. 1998;121(6):1013–1052
  53. Mori S, Wanaka S, Nagae-Poetscher LM, van Zijl PCM. MRI Atlas of Human White Matter. Amsterdam: Elsevier; 2005;
  54. Mori S, Kaufmann WE, Davatzikos C, Stieltjes B, Amodei L, Fredericksen K, et al. Imaging cortical association tracts in the human brain using diffusion-tensor-based axonal tracking. Magnetic Resonance in Medicine. 2002;47(2):215–223
  55. Nakayama N, Okumura A, Shinoda J, Yasokawa YT, Miwa K, Yoshimura SI, et al. Evidence for white matter disruption in traumatic brain injury without macroscopic lesions. Journal of Neurology, Neurosurgery and Psychiatry. 2006;77(7):850–855
  56. Newcombe F, Russell WR. Dissociated visual perceptual and spatial deficits in focal lesions of the right hemisphere. Journal of Neurology. 1969;32(2):73–78
  57. Niogi SN, Mukherjee P, Ghajar J, Johnson C, Kolster RA, Sarkar R, et al. Structural dissociation of attentional control and memory in adults with and without mild traumatic brain injury. Brain. 2008;131(12):3209–3221
  58. Oishi K, Faria AV, Van Zijl PCM, Mori S. MRI Atlas of Human White Matter. Elsevier; 2010;
  59. Petrides M, Tomaiuolo F, Yeterian EH, Pandya DN. The prefrontal cortex: Comparative architectonic organization in the human and the macaque monkey brains. Cortex. 2012;48(1):46–57
  60. Pontifex MB, O’Connor PM, Broglio SP, Hillman CH. The association between mild traumatic brain injury history and cognitive control. Neuropsychologia. 2009;47(14):3210–3216
  61. Powell HW, Parker GJ, Alexander DC, Symms MR, Boulby PA, Wheeler-Kingshott CA, et al. Imaging language pathways predicts postoperative naming deficits. Journal of Neurology, Neurosurgery and Psychiatry. 2008;79(3):327–330
  62. Rimrodt SL, Peterson DJ, Denckla MB, Kaufmann WE, Cutting LE. White matter microstructural differences linked to left perisylvian language network in children with dyslexia. Cortex. 2010;46(6):739–749
  63. Schmahmann JD, Pandya DN, Wang RP, Dai G, D’Arceuil HE, De Crespigny AJ, et al. Association fibre pathways of the brain: Parallel observations from diffusion spectrum imaging and autoradiography. Brain. 2007;130(3):630–653
  64. Senathi-Raja D, Ponsford J, Schoenberger M. Impact of age on long-term cognitive function after traumatic brain injury. Neuropsychology. 2010;24(3):336–344
  65. Sidaros A, Engberg AW, Sidaros K, Liptrot MG, Herning M, Petersen P, et al. Diffusion tensor imaging during recovery from severe traumatic brain injury and relation to clinical outcome: A longitudinal study. Brain. 2008;131(1):559–572
  66. Sidaros A, Skimminge A, Liptrot MG, Sidaros K, Engberg AW, Herning M, et al. Long-term global and regional brain volume changes following severe traumatic brain injury: A longitudinal study with clinical correlates. NeuroImage. 2009;44(1):1–8
  67. Sugiyama K, Kondo T, Higano S, Minoru E, Watanabe H, Shindo K, et al. Diffusion tensor imaging fiber tractography for evaluating diffuse axonal injury. Brain Injury. 2007;21(4):413–419
  68. Sundram F, Deeley Q, Sarkar S, Daly E, Latham R, Craig M, et al. White matter microstructural abnormalities in the frontal lobe of adults with antisocial personality. Cortex. 2012;48(2):199–212
  69. Tagliaferri F, Compagnone C, Korsic , Servadei , Kraus J. A systematic review of brain injury epidemiology in Europe. Acta Neurochirurgica (Wien). 2006;148(3):255–268
  70. Thiebaut de Schotten M, Dell’Acqua F, Valabregue R, Catani M. The monkey to human comparative anatomy of the frontal lobe association tracts. Cortex. 2012;48(1):82–96
  71. Thiebaut de Schotten M, ffytche DH, Bizzi A, Dell’Acqua F, Allin M, Walshe M, et al. Atlasing location, asymmetry and intersubject variability of white matter tracts in the human brain with MR diffusion tractography. NeuroImage. 2011;54(1):49–59
  72. Thiebaut de Schotten M, Kinkingnehun S, Delmaire C, Lehericy S, Duffau H, Thivard L, et al. Visualization of disconnection syndromes in humans. Cortex. 2008;44(8):1097–1103
  73. Thiebaut de Schotten M, Urbanski M, Duffau H, Volle E, Levy R, Dubois B, et al. Direct evidence for a parietal–frontal pathway subserving spatial awareness in humans. Science. 2005;309(5744):2226–2228
  74. Thomas C, Avidan G, Humphreys K, Jung KJ, Gao F, Behrmann M. Reduced structural connectivity in ventral visual cortex in congenital prosopagnosia. Nature Neuroscience. 2009;12(1):29–31
  75. Thomas C, Humphreys K, Jung KJ, Minshew N, Behrmann M. The anatomy of the callosal and visual-association pathways in high-functioning autism: A DTI tractography study. Cortex. 2011;47(7):863–873
  76. Thurman DJ, Coronado V, Selassie A. The epidemiology of TBI: Implications for public health. In: Brain Injury Medicine. New York: Demos; 2007;p. 45–56
  77. Trexler LE, Zappalà G. Re-examining the determinants of recovery and rehabilitation of memory defects following traumatic brain injury. Brain Injury. 1988;2(3):187–203
  78. Urbanski M, Thiebaut de Schotten M, Rodrigo S, Catani M, Oppenheim C, Touzè E, et al. Brain networks of spatial awareness: Evidence from diffusion tensor imaging tractography. Journal of Neurology, Neurosurgery and Psychiatry. 2008;79(5):598–601
  79. Urbanski M, Thiebaut de Schotten M, Rodrigo S, Catani M, Oppenheim C, Touzè E, et al. DTI-MR tractography of white matter damage in stroke patients with neglect. Experimental Brain Research. 2011;208(4):491–505
  80. Vernooij MW, Smits M, Wielopolski PA, Houston GC, Krestin GP, van der Lugt A. Fiber density asymmetry of the arcuate fasciculus in relation to functional hemispheric language lateralization in both right- and left-handed healthy subjects: A combined FMRI and DTI study. NeuroImage. 2007;35(3):1064–1076
  81. Wanaka S, Jiang H, Nagae-Poetscher LM, van Zijl PC, Mori S. Fiber tract-based atlas of human white matter anatomy. Radiology. 2004;230(1):77–87
  82. Wang JY, Bakhadirov K, Devous MD, Abdi H, McColl R, Moore C, et al. Diffusion tensor tractography of traumatic diffuse axonal injury. Archives of Neurology. 2008;65(5):619–626
  83. Wilde EA, McCauley SR, Hunter JV, Bigler ED, Chu Z, Wang ZJ, et al. Diffusion tensor imaging of acute mild traumatic brain injury in adolescents. Neurology. 2008;70(12):948–955
  84. Yeterian EH, Pandya DN, Tomaiuolo F, Petrides M. The cortical connectivity of the prefrontal cortex in the monkey brain. Cortex. 2012;48(1):58–81
  85. Yuan W, Holland SK, Schmithorst VJ, Waltz NC, Cecil KM, Jones BV, et al. Diffusion tensor MR imaging reveals persistent white matter alteration after traumatic brain injury experienced during early childhood. American Journal of Neuroradiology. 2007;28(10):1919–1925
  86. Zald DH, Andreotti C. Neuropsychological assessment of the orbital and ventromedial prefrontal cortex. Neuropsychologia. 2010;48(12):3377–3391
  87. Zappalà G. The frontal lobes: Executive and behavioural control of human reasoning. Implications for understanding brain injury. Rivista Italiana di Neurobiologia. 2008;54(4):195–202
  88. Zappalà G, Trexler LE. Quantitative and qualitative aspects of memory performance after minor head-injury. Archives of Clinical Neuropsychology. 1992;7(2):145–154

PII: S0010-9452(11)00208-5

doi: 10.1016/j.cortex.2011.06.020

Cortex
Volume 48, Issue 2 , Pages 156-165 , February 2012