Cortex
Volume 46, Issue 5 , Pages 595-601 , May 2010

‘Normal’ semantic–phonemic fluency discrepancy in Alzheimer's disease? A meta-analytic study

  • Keith R. Laws

      Affiliations

    • School of Psychology, University of Hertfordshire, UK
    • Corresponding Author InformationCorresponding author. School of Psychology, University of Hertfordshire, College Lane, Hatfield, Hertfordshire AL10 9AB, UK.
    • ,
  • Amy Duncan

      Affiliations

    • School of Psychology, University of Hertfordshire, UK
    • ,
  • Tim M. Gale

      Affiliations

    • School of Psychology, University of Hertfordshire, UK
    • Department of Psychiatry, QEII Hospital, HPFT, Welwyn Garden City, UK

Received 10 October 2008 ,Revised 3 April 2009 ,Accepted 13 April 2009.

References 

  1. Abrahams S, Goldstein LH, Simmons A, Brammer MJ, Williams SC, Giampietro VP, et al. Functional magnetic resonance imaging of verbal fluency and confrontation naming using compressed image acquisition to permit over responses. Human Brain Mapping. 2003;20:29–40
  2. Adlam A-LR, Bozeat S, Arnold R, Watson P, Hodges JR. Semantic knowledge in mild cognitive impairment and mild Alzheimer's disease. Cortex. 2006;42:675–684
  3. Amieva H, Jacqmin-Gadda H, Orgogozo JM, Le Carret N, Helmer C, Letenneur L, et al. The 9-year cognitive decline before dementia of the Alzheimer type: A prospective population-based study. Brain. 2005;128:1093–1101
  4. Ardila A, Ostrosky-Solis F, Rosselli M, Gomez C. Age-related cognitive decline during normal aging: The complex effect of education. Archives of Clinical Neuropsychology. 2000;15:495–514
  5. Bayles KA, Tomoeda CK, Trosset MW. Naming and categorical knowledge in Alzheimer's disease: The process of semantic memory deterioration. Brain and Language. 1990;39:498–510
  6. Braak H, Braak E. Neuropathological staging of Alzheimer-related changes. Acta Neuropathologica. 1991;82:239–259
  7. Braak H, Braak E. Evolution of the neuropathology of Alzheimer's disease. Acta Neurologica Scandinavica Supplementum. 1996;165:3–12
  8. Buckwalter JG, Rizzo AA, McCleary R, Shankle R, Dick M, Henderson VW. Gender comparisons of cognitive performances among vascular dementia, Alzheimer disease, and older adults without dementia. Archives of Neurology. 1996;53:436–439
  9. Buckwalter JG, Sobel E, Dunn ME, Diz MM, Henderson VW. Gender differences on a brief measure of cognitive functioning in Alzheimer's disease. Archives of Neurology. 1993;50:757–760
  10. Butters N, Granholm E, Salmon DP, Grant I, Wolfe J. Episodic and semantic memory: A comparison of amnesic and demented patients. Journal of Clinical and Experimental Neuropsychology. 1987;9:479–497
  11. Capitani E, Laiacona M, Basso A. Phonetically cued word-fluency, gender differences and aging: A reappraisal. Cortex. 1998;34:779–783
  12. Chen P, Ratcliff G, Belle SH, Cauley JA, DeKosky ST, Ganguli M. Patterns of cognitive decline in presymptomatic Alzheimer disease: A prospective community study. Archives of General Psychiatry. 2001;58:853–858
  13. Cohen J. Statistical Power Analysis for the Behavioral Sciences. 2nd ed.. Hillsdale, NJ: Lawrence Earlbaum Associates; 1988;
  14. Crossley M, D'Arcy C, Rawson SB. Letter and category fluency in community-dwelling Canadian seniors: A comparison of normal participants to those with dementia of the Alzheimer or vascular type. Journal of Clinical and Experimental Neuropsychology. 1997;19:52–62
  15. DerSimonian R, Laird N. Meta-analysis in clinical trials. Controlled Clinical Trials. 1986;7:177–188
  16. Folstein MF, Folstein SE, McHugh PR. Mini-mental state: A practical guide for grading the mental state of patients for the clinician. Journal of Psychiatric Research. 1975;12:189–198
  17. Fritsch T, McClendon MJ, Smyth KA, Ogrocki PK. Effects of educational attainment and occupational status on cognitive and functional decline in persons with Alzheimer-type dementia. International Journal of Geriatric Psychiatry. 2002;14:347–363
  18. Gladsjo JA, Schuman CC, Evans JD, Peavy GM, Miller SW, Heaton RK. Norms for letter and category fluency: Demographic corrections for age, education, and ethnicity. Assessment. 1999;16:147–178
  19. Gomez RG, White DA. Using verbal fluency to detect very mild dementia of the Alzheimer type. Archives of Clinical Neuropsychology. 2006;21:771–775
  20. Gourovitch ML, Kirkby BS, Goldberg TE. A comparison of rCBF patterns during letter and semantic fluency. Neuropsychology. 2000;14:353–360
  21. Hart RP, Kwentus JA, Taylor JR, Hamer RM. Productive naming and memory in depression and Alzheimer's type dementia. Archives of Clinical Neuropsychology. 1988;3:313–322
  22. Hedges LV, Olkin I. Statistical Methods for Meta-analysis. New York: Academic Press; 1985;
  23. Henderson VW, Buckwalter JG. Cognitive deficits of men and women with Alzheimer's disease. Neurology. 1994;44:90–96
  24. Henry JD, Crawford JR, Phillips LH. Verbal fluency performance in dementia of the Alzheimer's type: A meta-analysis. Neuropsychologia. 2004;42:1212–1222
  25. Hirono N, Mori E, Ishii H, Imamura T, Tanimukai S, Kazui H, et al. Neuronal substrates for semantic memory: A positron emission tomography study in Alzheimer's disease. Dementia and Geriatric Cognitive Disorders. 2001;12:15–21
  26. Hodges JR, Salmon DP, Butters N. Semantic memory impairment in Alzheimer's disease: Failure of access or degraded knowledge?. Neuropsychologia. 1992;30:301–314
  27. Joubert S, Felician O, Barbeaud EJ, Didic M, Poncet M, Ceccaldi M. Patterns of semantic memory impairment in Mild Cognitive Impairment. Behavioural Neurology. 2008;19:35–40
  28. Julious SA. Using confidence intervals around individual means to assess statistical significance between two means. Pharmaceutical Statistics. 2004;3:217–222
  29. Katzman R, Brown T, Thal LJ, Fuld PA, Aronson M, Butters N, et al. Comparison of rate of annual change of mental status score in four independent studies of patients with Alzheimer's disease. Annals of Neurology. 1988;24:384–389
  30. Keilp JG, Gorlyn M, Alexander GE, Stern Y, Prohovnik I. Cerebral blood flow patterns underlying the differential impairment in category vs. letter fluency in Alzheimer's disease. Neuropsychologia. 1999;37:1251–1261
  31. Kitabayashi Y, Ueda H, Tsuchida H, Iizumi H, Narumoto J, Nakamura K, et al. Relationship between regional cerebral blood flow and verbal fluency in Alzheimer's disease. Psychiatry and Clinical Neuroscience. 2001;55:459–463
  32. Kozora E, Cullum CM. Generative naming in normal aging: Total output and qualitative changes using phonemic and semantic constraints. The Clinical Neuropsychologist. 1995;9:313–320
  33. Laws KR. Gender differences in lexical size across categories. Personality and Individual Differences. 2004;36:23–32
  34. Laws KR, Adlington RL, Gale TM, Moreno-Martínez FJ, Sartori G. A meta-analytic review of category naming in Alzheimer's disease. Neuropsychologia. 2007;45:2674–2682
  35. Martin A, Fedio P. Word production and comprehension in Alzheimer's disease: The breakdown of semantic knowledge. Brain and Language. 1983;19:124–141
  36. Mathuranath PS, George A, Cherian PJ, Alexander A, Sarma SG, Sarma PS. Effects of age, education and gender on verbal fluency. Journal of Clinical and Experimental Neuropsychology. 2003;25:1057–1064
  37. McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM. Clinical diagnosis of Alzheimer's disease. Report of the NINCDS-ADRDA work group. Neurology. 1984;34:939–944
  38. McPherson S, Back C, Buckwalter JG, Cummings JL. Gender-related cognitive deficits in Alzheimer's disease. International Psychogeriatrics. 1999;11:117–122
  39. Monsch AU, Bondi MW, Butters N, Paulsen JS, Salmon DP, Brugger P, et al. A comparison of category and letter fluency in Alzheimer's disease and Huntington's disease. Neuropsychology. 1994;8:25–30
  40. Moreno-Martínez FJ, Laws KR, Schulz J. The impact of dementia, age and sex on category fluency: Greater deficits in women with Alzheimer's disease. Cortex. 2008;44:1256–1264
  41. Mortimer JA, Ebbitt BJ, Jun SP. Neuropsychological and behavioral predictors of decline in Alzheimer's disease. Journal of Clinical and Experimental Neuropsychology. 1991;13:109
  42. Mummery CJ, Patterson K, Hodges JR, Wise RJ. Generating ‘tiger’ as an animal name or a word beginning with T: Differences in brain activation. Proceedings of the Royal Society of London B. 1996;263:989–995
  43. Murphy KJ, Rich JB, Troyer AK. Verbal fluency patterns in amnestic mild cognitive impairment are characteristic of Alzheimer's type dementia. Journal of the International Neuropsychological Society. 2006;12:570–574
  44. Nebes RD, Martin DC, Horn LC. Sparing of semantic memory in Alzheimer's-disease. Journal of Abnormal Psychology. 1984;93:321–330
  45. Ober BA, Dronkers NF, Koss E, Delis DC, Friedland RP. Retrieval from semantic memory in Alzheimer's-type dementia. Journal of Clinical Experimental Neuropsychology. 1986;8:75–92
  46. Phillips L. Age and individual differences in letter fluency. Developmental Neuropsychology. 1999;15:249–267
  47. Pihlajamaki M, Tanila H, Hanninen T, Kononen M, Laakso M, Partanen K, et al. Verbal fluency activates the left medial temporal lobe: A functional magnetic resonance imaging study. Annals of Neurology. 2000;47:470–476
  48. Rascovsky K, Salmon DP, Hansen LA, Thal LJ, Galasko D. Disparate letter and semantic category fluency deficits in autopsy-confirmed frontotemporal dementia and Alzheimer's disease. Neuropsychology. 2007;21:20–30
  49. Ripich DN, Petrill SA, Whitehouse PJ, Ziol EW. Gender differences in language of AD patients: a longitudinal study. Neurology. 1995;45:299–302
  50. Rodriguez-Aranda C, Martinussen M. Age-related differences in performance of phonemic verbal fluency measured by controlled oral word association task (COWAT): A meta-analytic study. Developmental Neuropsychology. 2006;30:697–717
  51. Rosenberg MS, Adams DC, Gurevitch J. MetaWin: Statistical Software for Meta-analysis. Version 2.0 Sunderland, MA: Sinauer Associates; 2000;
  52. Rosenthal R. Meta-analytic Procedures for Social Research. Newbury Park, CA: Sage; 1991;
  53. Salmon DP, Heindel WC, Lange KL. Differential decline in word generation from phonemic and semantic categories during the course of Alzheimer's disease: Implications for the integrity of semantic memory. Journal of International Neuropsychological Society. 1999;5:692–703
  54. Satz P. Brain reserve capacity on symptom onset after brain injury: A formulation and review of evidence for threshold theory. Neuropsychology. 1993;7:273–295
  55. Scarmeas N, Albert SM, Manly JJ, Stern Y. Education and rates of cognitive decline in incident Alzheimer's disease. Journal of Neurology, Neurosurgery and Psychiatry. 2006;77:308–316
  56. Sherman AM, Massman PJ. Prevalence and correlates of category versus letter fluency discrepancies in Alzheimer's disease. Archives of Clinical Neuropsychology. 1999;14:411–418
  57. Soininen H, Helkala EL, Kuikka J, Hartikainen P, Lehtovirta M, Riekkinen PJ. Regional cerebral blood flow measured by 99mTc-HMPAO SPECT differs in subgroups of Alzheimer's disease. Journal of Neural Transmission. 1995;9:95–109
  58. Stern Y. What is cognitive reserve? Theory and research application of the reserve concept. Journal of the International Neuropsychological Society. 2002;8:448–460
  59. Stern Y, Albert S, Tang MX, Tsai WY. Rate of memory decline in AD is related to education and occupation: Cognitive reserve?. Neurology. 1999;53:1942–1957
  60. Suhr JA, Jones RD. Letter and semantic fluency in Alzheimer's, Huntington's, and Parkinson's dementias. Archives of Clinical Neuropsychology. 1998;13:447–454
  61. Thompson SG, Higgins JPT. How should meta-regression analyses be undertaken and interpreted?. Statistics in Medicine. 2002;21:1559–1573
  62. Tombaugh TN, Kozak J, Rees L. Normative data stratified by age and education for two measures of verbal fluency: FAS and animal naming. Archives of Clinical Neuropsychology. 1999;14:167–177
  63. Tomer R, Levin BE. Differential effects of aging on two verbal fluency tasks. Perceptual and Motor Skills. 1993;76:465–466
  64. Unverzagt FW, Hui SL, Farlow MR, Hall KS, Hendrie HC. Cognitive decline and education in mild dementia. Neurology. 1998;50:181–185
  65. Vogel A, Gade A, Stokolm J, Waldemar G. Semantic memory impairment in the earliest phases of Alzheimer's disease. Dementia and Geriatric Cognitive Disorders. 2005;19:75–81
  66. Wallentin M. Putative sex differences in verbal abilities and language cortex: A critical review. Brain and Language. 2009;108:175–183
  67. Wilson RS, Li Y, Aggarwal NT, Barnes LL, McCann JJ, Gilley DW, et al. Education and the course of cognitive decline in Alzheimer disease. Neurology. 2004;63:1198–1202

PII: S0010-9452(09)00148-8

doi: 10.1016/j.cortex.2009.04.009

Cortex
Volume 46, Issue 5 , Pages 595-601 , May 2010

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