The role of the striatum in phonological processing. Evidence from early stages of Huntington's disease

Abstract 

The linguistic role of subcortical structures such as the striatum is still controversial. According to the claim that language processing is subdivided into a lexical memory store and a computational rule system (Pinker, 1999) several studies on word morphology (e.g., Ullman et al., 1997) and on syntax (e.g., Teichmann et al., 2005) have suggested that the striatum is specifically dedicated to the latter component. However, little is known about whether the striatum is involved in phonological operations and whether its role in linguistic rule application generalizes to phonological processing. We investigated this issue by assessing perceptual compensation for assimilation rules in a model of striatal disorders, namely in the early stages of Huntington's disease (HD).

In Experiment 1 we used a same–different task with isolated words to evaluate whether phoneme perception is intact in HD. In Experiment 2 a word detection task in phrasal contexts allowed for assessing both phoneme perception and perceptual compensation for the French regressive assimilation rule. Results showed that HD patients have normal performance with both phoneme perception in isolated words and regressive assimilation rules. However, in phrasal contexts they display reduced abilities of phoneme discrimination.

These findings challenge the striatum-rule claim and suggest a more fine-grained function of striatal structures in linguistic rule processing. Alternative explanatory frameworks of the striatum-language link are discussed.

Keywords: Striatum, Language, Phonology, Rules, Huntington's disease